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The Author of nature has not given laws to the universe, which, like the institutions of men, carry in themselves the elements of their own destruction; he has not permitted in his works any symptom of infancy or of old age, or any sign by which we may estimate either their future or their past duration. He may put an end, as he no doubt gave a beginning, to the present system at some determinate period of time; but we may rest assured, that this great catastrophe will not be brought about by the laws now existing, and that it is not indicated by any thing which we perceive.
— John Playfair
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The constancy of the internal environment is the condition for free and independent life: the mechanism that makes it possible is that which assured the maintenance, with the internal environment, of all the conditions necessary for the life of the elements.
— Claude Bernard
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