"There is a false moral imperative that seems to be all-around us that treatment of depression, the medications and so on, are an artifice, and that it's not natural. And I think that's very misguided. It would be natural for people's teeth to fall out, but there is nobody militating against toothpaste, at least not in my circles."

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Life creeps slowly upward.... When some forgotten inventor of the older world smote his rival or enemy with a branch of wood and found that it was good and thereafter made a practice of smiting rivals and enemies with branches of wood, then, and on that day, artificiality may be said to have begun. Then, and on that day, was begun a revolution destined to change the history of life. Then, and on that day, was laid the cornerstone of that most tremendous of artifices, CIVILIZATION!

— Jack London