"There was a time when she had indulged in the hypothetical for hours a day, plotting the map that had led her here. But no life is a line, and hers was an uneven orbit around a dark star, a moth circling a dead bulb, searching for the light it once held."

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[Locating, from scratch, the gene related to a disease is like] trying to find a burned-out light bulb in a house located somewhere between the East and West coasts without knowing the state, much less the town or street the house is on.

— Francis Collins