"Unless the structure of the nucleus has a surprise in store for us, the conclusion seems plain — there is nothing in the whole system of laws of physics that cannot be deduced unambiguously from epistemological considerations."

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Act as if you are going to live for ever and cast your plans way ahead. You must feel responsible without time limitations, and the consideration of whether you may or may not be around to see the results should never enter your thoughts.

— Hyman Rickover