"Various species of animals react differently to the same drug. Not only do the variations in the metabolism of a drug make it difficult to extrapolate results of animal experiments to man but they create a serious obstacle to the development of new therapeutic drugs."

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The excuse or toleration of cruelty upon any living creature by a woman is a deadly sin against the grandest force in nature - maternal love ... In not a single instance known to science has the cure of any human disease resulted necessarily from this fallacious method of research.

— Elizabeth Blackwell