"When knowledge becomes formulated into a science, then it does take on a life of it's own, often alien to the human spirit that conceived it."

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What I liked about Mulder was his quality of not caring what other people thought of him. He was very independent. He wasn't interested in women. I liked that. He had kind of an intellectual quest, but not a sexual quest. That was the challenge of Mulder. Here was a guy that got almost sexually excited about aliens. And I wanted to be able to do that!

— David Duchovny