"Research is a way of taking calculated risks to bring about incalculable consequences."

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I do not choose to be a common man…it is my right to be uncommon—if I can…I seek opportunity—not security…I want to take the calculated risk; to dream and to build, to fail and to succeed… to refuse to barter incentive for a dole… I prefer the challenges of life to the guaranteed existence, the thrill of fulfillment to the stale calm of utopias….

— Peter O'Toole