"There is no beauty like that which was spoiled by an accident; no accomplishments and graces are so to be envied as those that circumstances rudely hindered the development of."

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The number of possible "on-off" patterns of neuronal firing is immense, estimated as a staggering ten times ten one million times (ten to the millionth power). The brain is obviously capable of an imponderably huge variety of activity; the fact that it is often organized and functional is quite an accomplishment!

— Daniel J. Siegel