"The old fashioned family physician and general practitioner ... was a splendid figure and useful person in his day; but he was badly trained, he was often ignorant, he made many mistakes, for one cannot by force of character and geniality of person make a diagnosis of appendicitis, or recognize streptococcus infection."

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Few diseases present greater difficulties in the way of diagnosis than malignant endocarditis, difficulties which in many cases are practi- cally insurmountable. It is no disparagement to the many skilled physicians who have put their cases upon record to say that, in fully one-half the diagnosis was made post mortem.

— William Osler