"We remain of the view that in many areas of research we are still reliant on primates to achieve our goals for improving human health"

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A lot of science doesn't require big "ns" but if you're trying to understand something about human health and you're looking at interventions that are not going to be either killing you or making you live forever - they're going to have some tweaking on the outcome - you need big numbers or you don't have enough power.

— Francis Collins