"Work is the basis of living. I'll never retire. A man'll rust out quicker than he'll wear out."

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Since the idea that modification of synaptic function can provide a basis for memory arose shortly after the first anatomical description of the synapse a number of models (Hebb 1949 . . Hayek 1952 . . Kendel 1981) have been proposed in which various cognitive activities are represented by combinations of the firing patterns of individual neurons.

— Gerald Edelman