"Small science, which includes most research in the life sciences all over the world, is science directed usually by an individual senior scientist and a small team of junior associates, perhaps three, ten, fifteen, something in that order."

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I haven't a single friend; I must live alone. But well I know that God is nearer to me than to the others of my art; I associate with Him without fear, I have always recognized and understood Him, and I have no fear for my music,-it can meet no evil fate. Those who understand it must become free from all the miseries that the others drag with them.

— Ludwig van Beethoven