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"Science is objective. And in my view we cannot take any experimental results seriously except in the light of good explanations of them."

— David Deutsch
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We should get used to the idea that we'll probably never be able to find - and confirm - a good explanation of the ultimate origin of the universe, though I see no reason to believe that we can't press much further on this question than we have managed to date.

— Daniel Dennett

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Where we have good, testable explanations, they then have to be tested, and we drop the ones that fail the tests.

— David Deutsch

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