"It's a closing of the mind that happens when you want to be lazy and go with the easiest answers, like the media do all the time in their sound bytes."

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It's not like you're closing the old doors and that investigators working away in a laboratories on a unique hypothesis are no longer needed. My gosh, they are indeed. But this becomes a real engine for hypothesis generation and even for proof if you have interventions that you can carry out in this kind of large scale and conduct them in a rigorous way. I guess, yeah, it's different. But it's different in a good way.

— Francis Collins