"Of the many species that have existed on earth - estimates run as high as fifty billion - more than ninety-nine per cent have disappeared. In the light of this, it is sometimes joked that all of life today amounts to little more than a rounding error."

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Modern statisticians are familiar with the notion that any finite body of data contains only a limited amount of information on any point under examination; that this limit is set by the nature of the data themselves, and cannot be increased by any amount of ingenuity expended in their statistical examination: that the statistician's task, in fact, is limited to the extraction of the whole of the available information on any particular issue.

— Ronald Fisher