"With the departure of Congressman Neil Abercrombie (D), who is running for the governorship of Hawaii, and with the tragic and very sad passing of my personal friend Jack Murtha (D-Pa.), mine is now the deciding vote on the health care bill and this administration and this House leadership have said, quote-unquote, they will stop at nothing to pass this health care bill. And now they’ve gotten rid of me and it will pass. You connect the dots."

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Consider the clinicaltrials by which drugs are tested in human subjects.5 Before a new drug can enter the market, its manufacturer must sponsor clinicaltrials to show the Food and Drug Administration that the drug is safe and effective, usually as compared with a placebo or dummy pill. The results of all the trials (there may be many) are submitted to the FDA, and if one or two trials are positive—that is, they show effectiveness without serious risk—the drug is usually approved, even if all the other trials are negative.

— Marcia Angell