"The problem is compounded by the fact that the connection between cause and effect seems so improbable. By turning on the lights, filling the kettle, taking the children to school, driving to the shops, we are condemning other people to death. We never chose to do this. We do not see ourselves as killers. We perform these acts without passion or intent."

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General Systems Theory, a related modern concept [to holism], says that each variable in any system interacts with the other variables so thoroughly that cause and effect cannot be separated. A simple variable can be both cause and effect. Reality will not be still. And it cannot be taken apart! You cannot understand a cell, a rat, a brain structure, a family, a culture if you isolate it from its context. Relationship is everything.

— Marilyn Ferguson