"If Washington were President now, he would have to learn our ways or lose his next election. Only fools and theorists imagine that our society can be handled with gloves or long poles. One must make one's self a part of it. If virtue won't answer our purpose, we must use vice, or our opponents will put us out of office, and this was as true in Washington's day as it is now, and always will be."

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When a scientist doesn't know the answer to a problem, he is ignorant. When he has a hunch as to what the result is, he is uncertain. And when he is pretty darn sure of what the result is going to be, he is still in some doubt. We have found it of paramount importance that in order to progress we must recognize our ignorance and leave room for doubt. Scientific knowledge is a body of statements of varying degrees of certainty - some most unsure, some nearly sure, but none absolutely certain.

— Richard P. Feynman