"I thrive best on solitude. If I have had a companion only one day in a week, unless it were one or two I could name, I find that the value of the week to me has been seriously affected. It dissipates my days, and often it takes me another week to get over it."

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Speaking one day to Monsieur de Buffon, on the present ardor of chemical inquiry, he affected to consider chemistry but as cookery, and to place the toils of the laboratory on the footing with those of the kitchen. I think it, on the contrary, among the most useful of sciences, and big with future discoveries for the utility and safety of the human race.

— Thomas Jefferson