"It is better not to apply any treatment in cases of occult cancer; for if treated (by surgery), the patients die quickly; but if not treated, they hold out for a long time."

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Smoke.. makes a kitchen also oftentimes in the inward parts of men, soiling and infecting them, with an unctuous and oily kinde of Soote as hath been found in some great Tobacco takers, that after their death were opened.

— King James I