"The wonderful structure of the animal system will probably never permit us to look upon it as a merely physical apparatus, yet the demands of science require that the evidently magnified principles of vitality should be reduced to their natural spheres, or if truth requires, wholly subverted in favor of those more cognizable by the human understanding. The spirit of the age will not tolerate in the devotee of science a quiet indifference."

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One can truly say that the irresistible progress of natural science since the time of Galileo has made its first halt before the study of the higher parts of the brain, the organ of the most complicated relations of the animal to the external world. And it seems, and not without reason, that now is the really critical moment for natural science; for the brain, in its highest complexity-the human brain-which created and creates natural science, itself becomes the object of this science.

— Ivan Pavlov