"I think you have waves of awareness and one of the things that I found with grief was actually - I was well prepared for it by the cyclicality of my manic depressive illness because I was used to things coming and going and so forth."

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I think that for thousands of years people have made the observation that there are certain kinds of extreme depressive states that seem to be more likely to produce philosophers, people in the arts, unusually brilliant scientists.

— Kay Redfield Jamison