"When things go awry, trust powers the generators until the problem is fixed."

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Preconceived ideas are like searchlights which illumine the path of the experimenter and serve him as a guide to interrogate nature. They become a danger only if he transforms them into fixed ideas-this is why I should like to see these profound words inscribed on the threshold of all the temples of science: 'The greatest derangement of the mind is to believe in something because one wishes it to be so.'

— Louis Pasteur