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The way to do great science is to stay away from subjects that are overpopulated, and go to the frontiers.
— James D. Watson
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Most old cities are now sclerotic machines that dispense known qualities in ever-greater quantities, instead of laboratories of the uncertain. Only the skyscraper offers business the wide-open spaces of a man-made Wild West, a frontier in the sky.
— Rem Koolhaas
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