"Of all the wonderful things that men and women share, shoes, tragically, are not one of them. This is because men lack the shoe chromosome."

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THE NOTE said the first clue was "in the big one." I looked at the jumble of letters that followed, and I saw no pattern. Not such a surprise, since I was missing the puzzle chromosome and couldn't do puzzles designed for nine-year-olds.

— Janet Evanovich