"I like to quote Homer Simpson: 'I'm like a chocoholic except for alcohol.' I come from a long line of alcoholics. It's funny because when I first started making records, I was at the tail end of a period of sobriety, so I somehow got this reputation as Captain Sober."

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I wanted to write a book that imagined where advances in the study of genetics might lead us. Holman was the first character who came to me: I envisaged the misshapen offspring of beautiful, wealthy parents. Then I realised that he bore a striking resemblance to Toulouse-Lautrec. I developed that, made Holman an alcoholic who lives among hookers, an artist tortured by his disability.

— Jonathan Trigell