"Tell me, was I the sort of person who took your elbow when cars passed on the street, touched your cheek while you talked, combed your wet hair, stopped by the side of the road in the country to point out certain constellations, standing behind you so that you had the advantage of leaning and looking up?"

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Manic-depression distorts moods and thoughts, incites dreadful behaviors, destroys the basis of rational thought, and too often erodes the desire and will to live. It is an illness that is biological in its origins, yet one that feels psychological in the experience of it, an illness that is unique in conferring advantage and pleasure, yet one that brings in its wake almost unendurable suffering and, not infrequently, suicide.

— Kay Redfield Jamison