"A few years ago, the Bose Acoustics Corporation had a new product, the Bose Wave Music System. And their ad campaign for it was not successful until they changed one thing. At the top of the ad they said, "Hear what you've been missing." And that caused the skyrocketing of the interest in purchasing of the product. Why? Because with something new, people are uncertain, and when they are uncertain, they want to avoid losses."

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In 1999, Purdue Pharma the maker of OxyContin went on a massive marketing campaign. Back then, prescription opioids were only used in extreme cases - post surgery, end of life care, cancer pain. We use a clip from an ad in the film where they had a doctor saying, "Less than 1 percent of people who use prescription opioid long-term will become addicted" - that changed the mindset of physicians across the country.

— Perri Peltz