"Shall we ever live to see the following wise prohibition - the audience is forbidden to smoke and the masters are forbidden to 'smoke out' the audience by playing exchanging variations?"

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Progress is achieved by exchanging our theories for new ones which go further than the old, until we find one based on a larger number of facts. ... Theories are only hypotheses, verified by more or less numerous facts. Those verified by the most facts are the best, but even then they are never final, never to be absolutely believed.

— Claude Bernard