"The question of how the ebb and flow of a highly developed mind can be catered to by a physical brain, and the related question of how the one impacts the other, are the hardest-ever challenges to human ingenuity and imagination."

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The most obvious feature of the brain is that it is not homogeneous, but composed of different regions. There are no intrinsic moving parts, no obvious way of knowing where to start to understand what is actually happening, or what functions are taking place.

— Susan Greenfield, Baroness Greenfield