"We should cultivate the optimistic temperament, and endeavour to see the good that dwells in everything. If we sit down and lament over the imperfection of our bodies and our minds, we profit nothing; it is the heroic endeavour to subdue adverse circumstances that carries our spirit upward."

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To stop short in any research that bids fair to widen the gates of knowledge, to recoil from fear of difficulty or adverse criticism, is to bring reproach on science. There is nothing for the investigator to do but go straight on, 'to explore up and down, inch by inch, with the taper his reason;' to follow the light wherever it may lead, even should it at times resemble a will-o'-the-wisp.

— William Crookes