"In 1492 Columbus knew less about the far Atlantic than we do about the heavens, yet he chose not to sail with a flotilla of less than three ships. . . . So it is with interplanetary exploration: it must be done on the grand scale."

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Shortly after Christopher Columbus and his sailors returned from their voyage to the New World, a horrifying new disease began to make its way around the Old. The "pox," as it was often called, erupted with dramatic severity.

— Peter Lewis Allen