"The self-same atoms which, chaotically dispersed, made the nebula, now, jammed and temporarily caught in peculiar positions, form our brains; and the 'evolution' of brains, if understood, would be simply the account of how the atoms came to be so caught and jammed."

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Pauling was shocked by the freedom with which the X-ray crystallographers of the time, including particularly Astbury, played with the intimate chemical structure of their models. They seemed to think that if the atoms were arranged in the right order and about the right distance apart, that was all that mattered, that no further restrictions need to be put on them.

— John Desmond Bernal