"Big Bang Theory' is not my kind of show. It's not my humor. I don't like multicam comedies. I don't want an audience to tell me when to laugh."

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In 50 years - or 20 years, or 200 years - our current epistemic horizon (the Big Bang, roughly) may look as parochial as the horizon Newton had to settle for in his day, but no doubt there will still be good questions whose answers elude us.

— Daniel Dennett