"Why is it that all those who have become eminent in philosophy, politics, poetry, or the arts are clearly of an atrabilious temperament and some of them to such an extent as to be affected by diseases caused by black bile?"

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Mad; adj. Affected with a high degree of intellectual independence; not conforming to standards of thought, speech, and action derived by the conformants from study of themselves; at odds with the majority; in short, unusual. It is noteworthy that persons are pronounced mad by officials destitute of evidence that they themselves are sane.

— Ambrose Bierce