"It's clear that there has to be some play between the vitality of invention in economic life and some regulation of it, and in some ways the great ideological wars of the 20th century that cost so many lives had to do with whether to have managed economies directed by government or economies directed by the free movement of capital, which is only partially subject to government regulation."

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The two explorers are given fictional names. But as in real life, they travel to the Amazon roughly a generation apart, in the early-to-mid 20th century. In the film, they're both guided by Karamakate, as a young man early in the story and later as an old shaman. He and the outsiders share a desire for knowledge - self knowledge and an understanding of the world around them, says the film's co-screenwriter, Jacques Toulemonde.

— Tom Cole