"The two explorers are given fictional names. But as in real life, they travel to the Amazon roughly a generation apart, in the early-to-mid 20th century. In the film, they're both guided by Karamakate, as a young man early in the story and later as an old shaman. He and the outsiders share a desire for knowledge - self knowledge and an understanding of the world around them, says the film's co-screenwriter, Jacques Toulemonde."