"I speak a lot about what I call "the trance of unworthiness" which is really epidemic in our culture, this sense of "I'm not enough," or "something's wrong with me." Most of us have some level of it because our culture has all these standards (handed down through our families) of what it means to be okay."

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Since the show [Helix] is based in real science, there are real-life epidemic scares out there, throughout history, where there are these huge viruses that have wiped out huge populations. So, we're dealing with something that the CDC hasn't seen before, but it comes from a virus. That's something that's based in reality, and then you put the science fiction on that and it's a really interesting combination.

— Kyra Zagorsky